@VJV The biggest problem with hypo is resistant strains of ich have been proven to exist. Quote below taken from this source: http://edis.ifas.ufl.edu/fa164
However, on the plus side research has showed hyposalinity at 15 ppt for 2 days eliminated juvenile and adult flukes. When maintained for 5 days, egg hatching was prevented. So, no need to treat with Prazipro beforehand if doing hypo.![Wink ;) ;)](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
More recently, studies have demonstrated different salinity tolerances among strains of Cryptocaryon. Yambot (2003) described one Taiwanese outbreak occurring in sea bream Sparus sarba at a salinity of 5 g/L, and another outbreak in sea perch Lates calcarifer occurring at a salinity of 10 g/L. These two strains were successfully propagated in the laboratory at 7 and 10 g/L, respectively, and are well below previously documented preferred salinities.
However, on the plus side research has showed hyposalinity at 15 ppt for 2 days eliminated juvenile and adult flukes. When maintained for 5 days, egg hatching was prevented. So, no need to treat with Prazipro beforehand if doing hypo.