Jay Hemdal
10K Club member
- Review score
- +0 /0 /-0
Staff member
Forum Moderator
Partner Member 2023
R2R Supporter
R2R Excellence Award
Expert Contributor
Article Contributor
Fish Medic
- Joined
- Jul 31, 2020
- Messages
- 19,471
- Reaction score
- 19,602
- Review score
- +0 /0 /-0
- Location
- Dundee, MI
Out of curiosity, why are you ok with PZQ?
You will read a lot about "Prazi resistant flukes". Indeed, in some aquariums, PZQ stops working after multiple doses. I had seen that myself, and at first attributed it to "acquired resistance". However, I noticed moving the fish to a new tank and treating them again worked! Years later, the researchers at Disney confirm that it is bacterial degradation of the PZQ, it becomes greater with every dose:
Praziquantel degradation in marine aquarium water
Praziquantel (PZQ) is a drug commonly utilized to treat both human schistosomiasis and some parasitic infections and infestations in animals. In the aquarium industry, PZQ can be administered in a “bath” to treat the presence of ectoparasites ...
www.ncbi.nlm.nih.gov
Jay