I can help with this one but no guru. You can remove the solder pads but not the resistors. The resistors are always connected directly to pins on pca9685 via the pads. The solder pads let 5v through and pull up the line changing the address. So the bottom traces going to solder pads from pca9685 would need to be re-routed to the resistors and then add 5v to whatever lines you want to change the address, the many combinations is why it has so many addresses.
Here's the schematic, you can see how it's wired.
I thought I read somewhere that if you weren't going to use the address pads, you could tie the address pins to ground for the default address. just can't leave the floating. Thats what I did on the first board I designed and it seemed to work just fine. I can't find where I read that now...