I recently got flaming prawn gobies and a new biota manderin baby. Right before getting them my brain went alittle crazy like it does thinking. I know biota voids a warranty for drip acclimating your manderin and the research is understandable about the harmful affects of ammonium converting back to harmful ammonia but my theory is the use of prime. But this is were I think my thoughts differ from the other thread on prime use and I want to check and see what other reefers thought on the subject. My thought is treating the incoming tank with prime prior to the drip starting. Because it seems it would be easier to get the dosage right for the gallons in the tank vs how much prime you would need for a bag of water. Then as you drip acclimate the water in the bag in theory could convert any harmful ammonia or prevent it from converting. I did not drip acclimate my fish but I added the prime in my tank while the temperature was acclimating then I took out so much water and replaced with my tank water treated with prime for 45 minutes. It seemed with the addition of prime to the tank water that my flaming prawns and baby mandy seemed much more responsive with less stress.