Also, i know each fish is a different size or weight and it is impossible to get an accurate measurement into each fish, but each fish only eats the amount of food its own body can handle so im thinking they will get a close to appropriate amount for their size. Or close to it.Sorry to hear it is spreading, that is unusual.
Metroplex needs to be dosed at a therapeutic rate, you cannot just mix some in with the food - your dose might be too low or too high. One dose is 100mg metro per kg of fish mass. That is very difficult to calculate. Another dose is 1/2 to 1% in the food by weight and feed that to the fish daily for three days. Trouble is, metro is very bitter, and when you get up around 1%, the fish stop eating it.
Here is an article on medicated foods:
Proper Dosing of Medicated Foods
This article offers information about developing medicated foods for aquarium fishwww.reef2reef.com
Jay