Chloroquine phosphate

raultsu · Mar 17, 2016

dangros said:
That's hopeful news. I picked up another 10g tank at lunch time and will xfer the tang tonight. As for feeding this guy, I will pick up some red titan macro from a local reefer (will put in new QT tonight) and ordered some Gracilaria. It will be much easier to see if macro is being consumed. I've already switched to rod's herbivore which I occasionally mix with mysis. I put the mysis on a paper towel and let it defrost. That way, the extra liquid gets absorbed in the towel instead of polluting the tank.
I'm throwing everything at this guy to get him back!

Try Purple Algae. i have a Bristletooth in CP right now and he wasn't eating. I put purple algae in the tank and he loves it

cmcoker · Mar 17, 2016

Humblefish said:
You never want to mix Prazipro with CP.

Why is this? Is it an issue with the other ingredients besides praziquantil?

the quote from alprazo in the 2nd post of this thread says,
Compatible with:
Praziquantil - YES (the known interaction has to do with cytochrome P450 in the first pass, hepatic metabolism of praziquantil and is not relevant when treating in bath formulation)

Humblefish · Mar 17, 2016

cmcoker said:
Why is this? Is it an issue with the other ingredients besides praziquantil?

the quote from alprazo in the 2nd post of this thread says,
Compatible with:
Praziquantil - YES (the known interaction has to do with cytochrome P450 in the first pass, hepatic metabolism of praziquantil and is not relevant when treating in bath formulation)

It's the Oxybispropanol (solubilizing agent) found in Prazipro that's the problem. Sometimes when you mix this with other medications (like CP), the interaction causes a bacterial bloom to occur which starves oxygen out of the water. I've even seen mild causes of this occur when mixing Prazipro with copper, but it wasn't bad enough to worry about. However, one time I mixed Prazipro with CP, and within 30 mins the water was so cloudy you couldn't even see into the tank. I lost a CBB that day (asphyxiation), and just barely saved a Chevron Tang that I had to immediately relocate to my frag tank.

You can, however, mix powder praziquantel (ex. API General Cure) with CP without issue. Because there is no solubilizing agent present to cause a negative interaction. The downside to using powder prazi is it takes longer to fully dissolve and you must dose 2x over a 48 hr period. So, not as effective for deworming as using liquid Prazipro which allows you to dose the full amount all in one shot.

cmcoker · Mar 18, 2016

Ok, i had just gone off of the praziquantil being ok in that post and added prazipro about 48hrs ago to my qt running with NLS ick shield powder. No problem so far...

Humblefish · Mar 18, 2016

cmcoker said:
Ok, i had just gone off of the praziquantil being ok in that post and added prazipro about 48hrs ago to my qt running with NLS ick shield powder. No problem so far...

I had mixed Prazipro & CP 3-4 times previously without issue. Then I had that one problem and haven't done it since. I did a little research and saw other people had the same issue, but it doesn't seem to happen every time for some reason. Further researched pinned down the culprit to specifically being the Oxybispropanol found in Prazipro.

cmcoker · Mar 18, 2016

Humblefish said:
I had mixed Prazipro & CP 3-4 times previously without issue. Then I had that one problem and haven't done it since. I did a little research and saw other people had the same issue, but it doesn't seem to happen every time for some reason. Further researched pinned down the culprit to specifically being the Oxybispropanol found in Prazipro.

Good to know, I'll use api if I need to combine in the future. I am gonna transfer out of Ick shield to a clean QT on Sunday, so next dose of prazipro will be only med in tank for 2nd dose

Reefahholic · Mar 18, 2016

Humblefish, great to see you here still fighting the battle. We need to get Snorvich over here too.

Humblefish · Mar 18, 2016

Reefahholic said:
Humblefish, great to see you here still fighting the battle. We need to get Snorvich over here too.

That would be great! I would like to see ThRoewer posting over here as well, as his beliefs/methods differ from mine. But I think our contrasts would be beneficial for this forum.

mcarroll · Mar 18, 2016

dangros said:
The water is starting to get cloudy and in spite of feeding small amounts 1/day, there is a good amount of junk accumulating in the 10g tank.
Even though the badge shows no ammonia, the water quality must be deteriorating. How should I proceed?

I know this is kinda got overlooked and is a little stale now in your storyline, but your instincts were correct...

Keep the QT detritus-free.
Don't leave uneaten food longer than an hour, ideally, but definitely no longer than a day. E.g. If you feed in the morning, remove any uneaten food no later than before you go to bed that night.

Everything about QT is stressful to the fish, especially the chemical and antibiotic treatments, so keeping after these housekeeping details so that there aren't additional stresses added is important!

Reefahholic · Mar 18, 2016

Humblefish said:
That would be great! I would like to see ThRoewer posting over here as well, as his beliefs/methods differ from mine. But I think our contrasts would be beneficial for this forum.

I like to hear all angles and prospectives. I think it's great that everybody has their own opinions. The essences of education is to consider all view points and seek for the truth! Furthermore, I think both of you guys have given some great advice over the years and have helped multiple hobbyist overcome some nasty marine parasites. That said, we're fortunate to have you here at R2R and I look forward for Snorvich's arrival. Randy Farley has made it over.

raultsu · Mar 25, 2016

Whats the recommended process after the 30 days of CP? Do you just add fish to display or should CP be removed using carbon then add fish to display?

Humblefish · Mar 25, 2016

raultsu said:
Whats the recommended process after the 30 days of CP? Do you just add fish to display or should CP be removed using carbon then add fish to display?

If QT is complete, just add the fish to your DT without lowering the CP level beforehand. However, if you still need to use Prazipro in order to deworm; run carbon / do water changes to remove the CP first.

dangros · Mar 27, 2016

The Hippo Tang continues to live on but the white splotches are still on it. I would say that at this point, it survived the CP and Kanaplex treatment.
I finally caught him eating by setting up a cam:
At this point, I'm wondering if the splotches are simply stress spots. As you can see, it swims around fine. Since I only have a 90g, I'm wondering if I should simply give the tang away and find one more suitable for such a "small" space.

dangros said:
That's hopeful news. I picked up another 10g tank at lunch time and will xfer the tang tonight. As for feeding this guy, I will pick up some red titan macro from a local reefer (will put in new QT tonight) and ordered some Gracilaria. It will be much easier to see if macro is being consumed. I've already switched to rod's herbivore which I occasionally mix with mysis. I put the mysis on a paper towel and let it defrost. That way, the extra liquid gets absorbed in the towel instead of polluting the tank.
I'm throwing everything at this guy to get him back!

Humblefish · Mar 27, 2016

@dangros Hippo Tangs do sometimes get these white splotches (stress spots). Maybe that's what you are seeing?

dangros · Mar 27, 2016

Possibly. I'll try to take a clear detailed pic tomorrow.

dangros · Mar 27, 2016

One other thing. I realized that i never put in the sponge to seed bacteria. Maybe that somehow contributed to his survival of cp?

raultsu · Mar 31, 2016

Humblefish said:
If QT is complete, just add the fish to your DT without lowering the CP level beforehand. However, if you still need to use Prazipro in order to deworm; run carbon / do water changes to remove the CP first.

Ok, just did a 75% water change and added a carbon cartridge/filter. How long should I wait to start Prazipro?

Humblefish · Mar 31, 2016

raultsu said:
Ok, just did a 75% water change and added a carbon cartridge/filter. How long should I wait to start Prazipro?

24 hrs after running carbon.

dangros · Apr 5, 2016

Just to update my tang situation: The tang's white marks mostly vanished. It was in QT for almost a month. It continued to be wildly shy but started to look quite skinny. So I took it out and put it back in my DT. It now looks like it's made a full recovery and is even coming out to eat when fed. It's still shy but not as much as it was pre-QT and during QT. It has even fattened back up already. It did have some white fuzz looking thing around the base of its tail but I wasn't able to capture a good image of it. That seems to be gone too.