I am totally messing. I always overbuild. I always feel worried about stuff falling apart. I even used nails and screws when assembling.Nothing wrong with 2x4 at all, especially from a strength point. I think you'd be able to park a whole truck stop worth of tractor trailers on top of your stand . I have a small house and having that extra room to store all the reef keeping gear is essential. Same reason I had the stand bigger from to back by like 7" and side to side by another 2"ish. Plus the added benefit of a working space when testing water, etc.
Think of it like this - where you have 2x8's - thedoubled up 3/4" on mine is only 1-1/2". Thats 6"+ of lost real estate. Plus the sides that's another 3"+ in both directions vertically from the 2x4.
Another way to look at it is standard kitchen cabinets are basic 3/4" boxes at their core, with huge cut outs for doors and drawer, usually with no back. These can hold up fat chonks of thick granite no problem.
My design has a full back and a shelf that is screwed to all sides with extra supports underneath. Plus the base which has double up framing and cross braces underneath.
I did a bad job taking pics of the cabinet build because I was rushing to get it don't in a weekend using my old man's wood shop.
How do you feel about the back chamber on yours? I feel like the IM AIO have smaller compartments, but I also like that this maximizes display space.
The back chamber on mine is about 3.5in wide. I have been able to fit everything I need to in it so far, and do actually like the idea that I dont have to worry about an overflow overflowing if a pump dies, or snail gets stuck etc. I did have to figure out a separate ATO container.