My experiences treating rapid tissue necrosis in multiple SPS species with doxycycline and amoxicillin

[Cnidoblast]

I really still think Cipro would be the ideal choice for treating RTN:

From the CDC's website:




If it's good enough for the CDC to take note perhaps it's worth a try for this?

 

[TheDragonsReef]

Came across this thread while searching for ways to stop rtn. Are any of these products readily available or do they need prescriptions?

 

[weamdog]

Came across this thread while searching for ways to stop rtn. Are any of these products readily available or do they need prescriptions?

You can order from chewy with no prescription. Jury is still out on my 2 frags which is a good thing.

Fish Aid Antibiotics - Free shipping | Chewy

Shop Chewy for low prices and the best Fish Aid Antibiotics! We carry a large selection and the top brands like American Journey and more. Find everything you need in one place. FREE shipping on orders $49+ and the BEST customer service!

www.chewy.com

 

[TheDragonsReef]

You can order from chewy with no prescription. Jury is still out on my 2 frags which is a good thing.

which product? Thanks

 

[weamdog]

I ordered the amox and doxy myself.

 

[weamdog]

Here is an updated photo 2 weeks later. Not sure if the frag on the left has any life left, but pretty sure the right has polyps in the center yellowish section as i saw them a couple days ago. That was the frag that went first and appeared completely gone for like a week before amox.

Photos taken after lights out.

 

[JoshB94]

Update on my amoxicillin frags : all appear 100% loss. ICP results came back today with zero abnormalities (consistent with previous results besides previous zero iodine and strontium that are now detectable)

Convinced my losses are bacterial, Thinking I'll go ahead and try Cipro as I've lost about 5 more pieces probably 20 total in 2 months. No pests identified in "autopsy" with heavy pest dip.

 

[Courtney Aldrich]

I've attached a recent paper looking at antibiotic susceptibility of saltwater Vibrio Harveyi and related species. Doxycycline, ciprofloxacin and florfenicol are great, whereas most strains are resistant to amoxicillin.

 

[The Opinionated Reefer]

This is all fine and dandy but what about people who have stn on corals that all encrusted onto the rock work? How would treat it then? Is there no way to slather the base of an encrusted coral with some kind of antibiotic without having it spread through the tank?

 

[Dr. Jim]

I've attached a recent paper looking at antibiotic susceptibility of saltwater Vibrio Harveyi and related species. Doxycycline, ciprofloxacin and florfenicol are great, whereas most strains are resistant to amoxicillin.

That is an interesting study but, unless I missed it, nowhere did they mention drug dosages, durations, and route of administration. Seems like that would be rather important to mention when discussing their conclusions. (It would have also be helpful to us if they had given some guidelines as to how the fish were treated).

 

[SecondCityCorals]

This is all fine and dandy but what about people who have stn on corals that all encrusted onto the rock work? How would treat it then? Is there no way to slather the base of an encrusted coral with some kind of antibiotic without having it spread through the tank?

The solution is exactly what you think it is. Drastic. You'll have to break it off the rock.

 

[sdreef]

This is all fine and dandy but what about people who have stn on corals that all encrusted onto the rock work? How would treat it then? Is there no way to slather the base of an encrusted coral with some kind of antibiotic without having it spread through the tank?

I've attached a recent paper looking at antibiotic susceptibility of saltwater Vibrio Harveyi and related species. Doxycycline, ciprofloxacin and florfenicol are great, whereas most strains are resistant to amoxicillin.

Here is a possible in tank treatment regimen using cipro. The disease being treated is different, and I have not tried this myself, but it could apply in this situation if you are confident that you are dealing with a bacterial infection. The study above shows, many species of Vibrio are susceptible to cipro. Unfortunately without a culture or some type of diagnostic test, its hard to confirm which bacteria may be causing the infection, but this is one possible in tank treatment approach. The author, @AquaBiomics, also shares the impact on the tank's microbiome.

https://www.reef2reef.com/ams/exper...iotic-treatments-for-brown-jelly-disease.791/

 

[The Opinionated Reefer]

Cipro! That stuff nearly killed me. Affected the QT rate of my heart causing me to black out and nearly die and gave me joint pain forever after. Wouldn't mess with it in a tank.

 

[Enigma84]

So what amount of Doxycycline per amount of tank water and time are people having success with? More so for the author of the thread.

 

[Velcro]

Cipro! That stuff nearly killed me. Affected the QT rate of my heart causing me to black out and nearly die and gave me joint pain forever after. Wouldn't mess with it in a tank.

Well your corals don’t have a heart let alone a QTc interval, and also don’t have tendons to worry about so you might want to relax lol

 

[The Opinionated Reefer]

Well your corals don’t have a heart let alone a QTc interval, and also don’t have tendons to worry about so you might want to relax lol

The fish do though.

 

[Velcro]

The fish do though.

True, but if we are talking about bathing just the coral and returning it to the tank the fish will be exposed to about zero cipro lol

 

[The Opinionated Reefer]

I was talking about full tank treatments

 

[BurgerFish]

I found expired in 2020 amoxicillin. Mix 1000mg pil in 250ml of tank water.

Will see. I'll bath them 5-15 min a day.

 

[LimestoneCowboy]

I found expired in 2020 amoxicillin. Mix 1000mg pil in 250ml of tank water.

Will see. I'll bath them 5-15 min a day.

Any luck with this @BurgerFish ?