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The biggest problem with hyposalinity is hypo resistant strains of ich have been proven to exist. Hypo also doesn't treat velvet, which can look similar to ich in the early stages. Copper treats both, and as far as I am aware there are no copper resistant strains of ich that have been proven to exist.
There is conflicting views on this, but Metroplex is a newer medicine that claims to treat ich, and can actually be fed to fish while in the reef tank, and doesn't hurt coral.