Chloroquine phosphate

jasonrusso

2500 Club Member
View Badges
Joined
Apr 21, 2014
Messages
3,335
Reaction score
2,455
Location
Haverhill, MA
Rating - 0%
0   0   0
I did a 40% water change and rechecked and it’s at 1.87 now. I started running Rowphos.

80 day fallow is for ich and observation. The inverts I get come from a very reputable source with a dedicated invert system with no fish.

The corals I dip with coral Rx going into qt and revive going into display. The fallow period should protect me against ich which is key for me. Aiptasia isn’t pleasant but I can deal with it with peppermint shrimp. I didn’t have corals so I decided to take the CP route and make sure i start with a clean slate.

I’m running carbon and rowaphos and I assume with biweekly water changes and 80 days of carbon and gfo I should have a clean system.

Just gotta figure out what I would put in there as the canary say 2 weeks before others to make sure it’s all good.

So you put the corals in a QT and treated the DT? Did you have crypt before?
 

XLOR8T

Active Member
View Badges
Joined
Mar 22, 2018
Messages
212
Reaction score
118
Rating - 0%
0   0   0
So you put the corals in a QT and treated the DT? Did you have crypt before?

The corals are new so they are in QT to prevent crypt/ich/velvet. The inverts go in the same system. No fish so no host and hence the biological life cycle is broken.

I took the inverts to qt when I treated the DT. The emeralds did fine in treated water but snails were not feeling well. I saved all but 3 Trochus

GFO is working well after 24hrs PO4 is down to 1.47
 

ReefWithCare

Valuable Member
View Badges
Joined
Mar 3, 2016
Messages
1,059
Reaction score
723
Rating - 0%
0   0   0
Hi All,

So I found a source for CP and got the Cert of Analysis. It had a gigantic warning label on it that it is not to be used for human consumption or vet usage and the analysis was 100% :eek:

Is this stuff too pure for our usage? It's the only legit COA I have gotten. All the others were from China or the COA was from a Chinese Lab :mad:.

It's also just as expensive as buying from a Vet (If a vet would give me a script). I figured the high price is a good sign :).
 

ReefWithCare

Valuable Member
View Badges
Joined
Mar 3, 2016
Messages
1,059
Reaction score
723
Rating - 0%
0   0   0
I don't see how 100% pure is possible. Almost every med has fillers or binders.

But @Christoph or @Randy Holmes-Farley would know for sure.

Yea, it was almost too good to be true lol. The best I have seen from COAs has been 99.5%. It was really expensive as well.

But expensive kinda gives me piece of mind vs. the China Ebay sellers lol. It having a giant warning label for some strange reason made me feel better ;Bored
 
OP
OP
H

Humblefish

Dr. Fish
View Badges
Joined
Nov 9, 2014
Messages
22,424
Reaction score
34,869
Rating - 0%
0   0   0
Yea, it was almost too good to be true lol. The best I have seen from COAs has been 99.5%. It was really expensive as well.

But expensive kinda gives me piece of mind vs. the China Ebay sellers lol. It having a giant warning label for some strange reason made me feel better ;Bored

Wait until one of the above chime in; I could be wrong about the 100% purity thing.
 

drstardust

Well-Known Member
View Badges
Joined
Sep 3, 2017
Messages
680
Reaction score
1,209
Rating - 0%
0   0   0
Hi All,

So I found a source for CP and got the Cert of Analysis. It had a gigantic warning label on it that it is not to be used for human consumption or vet usage and the analysis was 100% :eek:

Is this stuff too pure for our usage? It's the only legit COA I have gotten. All the others were from China or the COA was from a Chinese Lab :mad:.

It's also just as expensive as buying from a Vet (If a vet would give me a script). I figured the high price is a good sign :).

Would you be willing to share your source?
 

ReefWithCare

Valuable Member
View Badges
Joined
Mar 3, 2016
Messages
1,059
Reaction score
723
Rating - 0%
0   0   0
Would you be willing to share your source?

It's a Lab that sells research material to institutions. They didn't seem to mind me buying from them - at least for now ;) . It's like $95 for 25 Grams :eek:. Around the price you get from a Vet --- but that purity at 100% seems scary and they have a huge warning label to not use it for human or vet usage o_O.

I've seen a lot of COA's from China and Taiwan with 99%+ --- but this lab grade stuff is very peace of mind if you don't paying the price --- assuming 100% purity is safe to use
 
Last edited:

drstardust

Well-Known Member
View Badges
Joined
Sep 3, 2017
Messages
680
Reaction score
1,209
Rating - 0%
0   0   0
It's a Lab that sells research material to institutions. They didn't seem to mind me buying from them - at least for now ;) . It's like $95 for 25 Grams :eek:. Around the price you get from a Vet --- but that purity at 100% seems scary and they have a huge warning label to not use it for human or vet usage o_O.

I've seen a lot of COA's from China and Taiwan with 99%+ --- but this lab grade stuff is very peace of mind if you don't paying the price --- assuming 100% purity is safe to use
Yeah. It doesn't make sense for an extra 1% purity, if in fact this is real, to make it more dangerous. They probably give that warning to cover their butt since it's not regulated by a pharmaceutical authority for commercial human/animal use.
 

Christoph

Active Member
View Badges
Joined
May 23, 2017
Messages
273
Reaction score
592
Location
Vienna, Austria
Rating - 0%
0   0   0
Hi everybody,

So I found a source for CP and got the Cert of Analysis. It had a gigantic warning label on it that it is not to be used for human consumption or vet usage and the analysis was 100%

"100%" pure might be a bit of an overstatement, since nearly everything has some degree of impurities. But to be honest, for our practical purposes it does not really matter if the used CP is 93%, 95%, 99% or 100% pure. Lets assume somebody is targeting for 10 mg/l CP concentration in a 100 l tank. It is assumed the CP is 100% pure, so 10*100 = 1000 mg CP is dosed. If the CP actually has only a purity of 93% (instead of the 100%) the actual amount of CP dosed would be 930 mg giving a concentration of 9.3 mg/l in the tank (instead of the aimed for 10 mg/l). This is still well within the therapeutic range, so there would be no practical consequences.

Have a good weekend!

Christoph
 

svogun

Active Member
View Badges
Joined
Jun 26, 2014
Messages
391
Reaction score
395
Location
Wallingford CT
Rating - 0%
0   0   0
Cayman chemical offers 25 g for 50 bucks indicating 100% purity but not for human or vet use. Might be worth contacting them to discuss.


"100%" pure might be a bit of an overstatement, since nearly everything has some degree of impurities. But to be honest, for our practical purposes it does not really matter if the used CP is 93%, 95%, 99% or 100% pure. Lets assume somebody is targeting for 10 mg/l CP concentration in a 100 l tank. It is assumed the CP is 100% pure, so 10*100 = 1000 mg CP is dosed. If the CP actually has only a purity of 93% (instead of the 100%) the actual amount of CP dosed would be 930 mg giving a concentration of 9.3 mg/l in the tank (instead of the aimed for 10 mg/l). This is still well within the therapeutic range, so there would be no practical consequences.

Have a good weekend!

Christoph[/QUOTE]
ayman
 

ReefWithCare

Valuable Member
View Badges
Joined
Mar 3, 2016
Messages
1,059
Reaction score
723
Rating - 0%
0   0   0
Cayman chemical offers 25 g for 50 bucks indicating 100% purity but not for human or vet use. Might be worth contacting them to discuss.


"100%" pure might be a bit of an overstatement, since nearly everything has some degree of impurities. But to be honest, for our practical purposes it does not really matter if the used CP is 93%, 95%, 99% or 100% pure. Lets assume somebody is targeting for 10 mg/l CP concentration in a 100 l tank. It is assumed the CP is 100% pure, so 10*100 = 1000 mg CP is dosed. If the CP actually has only a purity of 93% (instead of the 100%) the actual amount of CP dosed would be 930 mg giving a concentration of 9.3 mg/l in the tank (instead of the aimed for 10 mg/l). This is still well within the therapeutic range, so there would be no practical consequences.

Have a good weekend!

Christoph
ayman[/QUOTE]

They charge you $36 for shipping so it is actually more like $86 dollars [emoji28]
 
OP
OP
H

Humblefish

Dr. Fish
View Badges
Joined
Nov 9, 2014
Messages
22,424
Reaction score
34,869
Rating - 0%
0   0   0
Hi everybody,



"100%" pure might be a bit of an overstatement, since nearly everything has some degree of impurities. But to be honest, for our practical purposes it does not really matter if the used CP is 93%, 95%, 99% or 100% pure. Lets assume somebody is targeting for 10 mg/l CP concentration in a 100 l tank. It is assumed the CP is 100% pure, so 10*100 = 1000 mg CP is dosed. If the CP actually has only a purity of 93% (instead of the 100%) the actual amount of CP dosed would be 930 mg giving a concentration of 9.3 mg/l in the tank (instead of the aimed for 10 mg/l). This is still well within the therapeutic range, so there would be no practical consequences.

Have a good weekend!

Christoph

So, perhaps those who obtain CP from a questionable source (like eBay) should dose @ 15mg/L (60mg/gal). Since 10-20mg/L is the accepted range.
 

GoldeneyeRet

2500 Club Member
View Badges
Joined
Jul 7, 2016
Messages
3,079
Reaction score
11,184
Rating - 0%
0   0   0
So, perhaps those who obtain CP from a questionable source (like eBay) should dose @ 15mg/L (60mg/gal). Since 10-20mg/L is the accepted range.

That may help to address the purity issues with cp sourced from unreliable sources, but shelf life and uv exposure are still unknown.
 
Last edited:

ReefWithCare

Valuable Member
View Badges
Joined
Mar 3, 2016
Messages
1,059
Reaction score
723
Rating - 0%
0   0   0
Cayman chemical offers 25 g for 50 bucks indicating 100% purity but not for human or vet use. Might be worth contacting them to discuss.


"100%" pure might be a bit of an overstatement, since nearly everything has some degree of impurities. But to be honest, for our practical purposes it does not really matter if the used CP is 93%, 95%, 99% or 100% pure. Lets assume somebody is targeting for 10 mg/l CP concentration in a 100 l tank. It is assumed the CP is 100% pure, so 10*100 = 1000 mg CP is dosed. If the CP actually has only a purity of 93% (instead of the 100%) the actual amount of CP dosed would be 930 mg giving a concentration of 9.3 mg/l in the tank (instead of the aimed for 10 mg/l). This is still well within the therapeutic range, so there would be no practical consequences.

Have a good weekend!

Christoph
ayman[/QUOTE]
I'm a little confused by this - because this pretty much tells me that any source not named the Vet is okay as long as you have a COA that states the purity and you can adjust accordingly.

All COA's I have looked at have ranged from 95 - 100%
 

XLOR8T

Active Member
View Badges
Joined
Mar 22, 2018
Messages
212
Reaction score
118
Rating - 0%
0   0   0
Has anyone come up with a way to know if CP is completely out of a system? It’s been 4 weeks and 5 30% water changes, carbon for 1 week. Brown algae bloom (since skimmer is offline right now) just trying figure out how I could determine the cp is completely gone. Any work around test not for levels but for existence of the substance. The high phosphates are gone too thanks To Rowaphos. Down to 6ppb Phosphorus based on Hanna ULR.

Edit: it was display tank that was treated not qt.
 
OP
OP
H

Humblefish

Dr. Fish
View Badges
Joined
Nov 9, 2014
Messages
22,424
Reaction score
34,869
Rating - 0%
0   0   0
Has anyone come up with a way to know if CP is completely out of a system? It’s been 4 weeks and 5 30% water changes, carbon for 1 week. Brown algae bloom (since skimmer is offline right now) just trying figure out how I could determine the cp is completely gone. Any work around test not for levels but for existence of the substance. The high phosphates are gone too thanks To Rowaphos. Down to 6ppb Phosphorus based on Hanna ULR.

Edit: it was display tank that was treated not qt.

If you are seeing algae growth, then CP is mostly gone since it is a strong algaecide.

Whenever I wish to remove CP, I run carbon in a media reactor for 24-48 hours. I've read you can also use a UV sterilizer, but I'm not sure if I still believe that. In any case, without a spectrophotometer it's hard to say for sure that the medication is 100% out of the water. o_O
 

XLOR8T

Active Member
View Badges
Joined
Mar 22, 2018
Messages
212
Reaction score
118
Rating - 0%
0   0   0
If you are seeing algae growth, then CP is mostly gone since it is a strong algaecide.

Whenever I wish to remove CP, I run carbon in a media reactor for 24-48 hours. I've read you can also use a UV sterilizer, but I'm not sure if I still believe that. In any case, without a spectrophotometer it's hard to say for sure that the medication is 100% out of the water. o_O

I’ll be running Red Sea carbon until October 20 when the corals come out of qt and go into display. Just wanted to make sure it’s out by then. Doing big water changes too. 30% at a time.
 

GoldeneyeRet

2500 Club Member
View Badges
Joined
Jul 7, 2016
Messages
3,079
Reaction score
11,184
Rating - 0%
0   0   0
If you are seeing algae growth, then CP is mostly gone since it is a strong algaecide.

Whenever I wish to remove CP, I run carbon in a media reactor for 24-48 hours. I've read you can also use a UV sterilizer, but I'm not sure if I still believe that. In any case, without a spectrophotometer it's hard to say for sure that the medication is 100% out of the water. o_O

I agree, no practical way to know if CP is 100% removed. I also agree if you are seeing algea growth CP should be mostly gone.

Regarding UV, I am under the impression CP is only UV sensitive while in powdered form, am I mistaken?
 

drstardust

Well-Known Member
View Badges
Joined
Sep 3, 2017
Messages
680
Reaction score
1,209
Rating - 0%
0   0   0
I am under the impression CP is only UV sensitive while in powdered form, am I mistaken?

I was wondering about this as well. It has been discussed many times whether UV or visible light has any effect on CP. It keeps getting discussed without a clear consensus. Do you know more, @Humblefish ?
 
Back
Top