Prazipro treatment

Jax3545 · May 24, 2023

I dosed prazipro yesterday. I turned off the pump and let it sit in my sump for a few hours. Today I've noticed the fish are a bit more aggressive towards each other. The sailfin has checked the vlamingii several times, the Carkii are mega d**KS. The female was after my bt trigger. The foxface was doing weird swimming and kept running into things. The foxface also had cloudy "slime" floating behind its eyes. He is why I did prazipro, eyes were cloudy when all others were not. I managed to catch him and he's in qt.
So is the prazi creating an uncomfortable situation for the others as they are infected with flukes as well? How do I keep them from being reinfected in the dt?

MnFish1 · May 24, 2023

Jax3545 said:
I dosed prazipro yesterday. I turned off the pump and let it sit in my qt for a few hours. Today I've noticed the fish are a bit more aggressive towards each other. The sailfin has checked the vlamingii several times, the Carkii are mega d**KS. The female was after my bt trigger. The foxface was doing weird swimming and kept running into things. The foxface also had cloudy "slime" floating behind its eyes. He is why I did prazipro, eyes were cloudy when all others were not. I managed to catch him and he's in qt.
So is the prazi creating an uncomfortable situation for the others as they are infected with flukes as well? How do I keep them from being reinfected in the dt?

If you could send a picture that would be nice. I would wonder if it could be a bacterial infection as compared to fluke. Any other symptoms? Are you sure you dosed the Prazipro correctly for the volume in your tank? Do any of your fish have any other disease symptoms (beyond what you described - fast breathing, etc - were the rest of them quarantined)? Lastly you need to increase oxygen with Prazipro.

vetteguy53081 · May 24, 2023

Jax3545 said:
I dosed prazipro yesterday. I turned off the pump and let it sit in my qt for a few hours. Today I've noticed the fish are a bit more aggressive towards each other. The sailfin has checked the vlamingii several times, the Carkii are mega d**KS. The female was after my bt trigger. The foxface was doing weird swimming and kept running into things. The foxface also had cloudy "slime" floating behind its eyes. He is why I did prazipro, eyes were cloudy when all others were not. I managed to catch him and he's in qt.
So is the prazi creating an uncomfortable situation for the others as they are infected with flukes as well? How do I keep them from being reinfected in the dt?

How did you dose it and turning off the pumps was not good as Prazi has a glycol agent in the solution and needs to be diluted. The question is are they going nuts from solution, or is it because they are in a smaller tank being the quarantine tank with less cover.
The typical treatment for prazi is to be safe , dose at 80% of recommended and apply initial dosage known as an interval for 8 days, do a water change and do one more 8 day dose interval
Use airstone with prazi as it does reduce both oxygen and appetite

Crabby48 · May 24, 2023

Agree with Bette guy. Also if you have extra power head keep at surface

Jax3545 · May 24, 2023

I need to go back and edit. I dosed it in my sump and let it dissipate for a couple hours. Then ran the tank as usual.

MnFish1 · May 25, 2023

Jax3545 said:
I need to go back and edit. I dosed it in my sump and let it dissipate for a couple hours. Then ran the tank as usual.

But then the water from your sump went into your tank?

Jay Hemdal · May 25, 2023

There isn't anything about a prazi treatment that would make the fish more aggressive.

I'm not sure about the turning off the sump - no need to do that. Prazipro actually disperses as a fine suspension - it is best to add some to the sump and the rest to the tank itself. Always add extra aeration when dosing, and dose to the net volume of the tank, not its rated capacity. Here is the instructions I give for its use:

Prazipro
You can dose your DT with Prazipro, when done properly, it is safe for fish and invertebrates (clams may retract a bit during treatment, there are rare reports of feather duster worms being harmed). The dose works like this: Remove all chemical filtrants like carbon. Add an extra air stone to the tank. Run any protein skimmers, but don't collect the skimmate. Add a full dose of Prazipro to the net volume of the tank (usually about 85% of the "rated" tank volume). Wait 8 days, change 25% of the water and redose. Praziquantel breaks down in about 72 hours, the water change is just to reduce nutrients leftover from that.

Jay

Jax3545 · May 25, 2023

Jay Hemdal said:
There isn't anything about a prazi treatment that would make the fish more aggressive.

I'm not sure about the turning off the sump - no need to do that. Prazipro actually disperses as a fine suspension - it is best to add some to the sump and the rest to the tank itself. Always add extra aeration when dosing, and dose to the net volume of the tank, not its rated capacity. Here is the instructions I give for its use:

Prazipro
You can dose your DT with Prazipro, when done properly, it is safe for fish and invertebrates (clams may retract a bit during treatment, there are rare reports of feather duster worms being harmed). The dose works like this: Remove all chemical filtrants like carbon. Add an extra air stone to the tank. Run any protein skimmers, but don't collect the skimmate. Add a full dose of Prazipro to the net volume of the tank (usually about 85% of the "rated" tank volume). Wait 8 days, change 25% of the water and redose. Praziquantel breaks down in about 72 hours, the water change is just to reduce nutrients leftover from that.

Jay

Thank you! Everyone is normal today. I did manage to get the foxface in qt. I didn't like how his eyes looked. He's also too skinny so I'll get to fatten him up too. (Waters green from Rally. Pics from a month ago)

Jax3545 · May 26, 2023

Back again. I did a 2nd dose of prazipro a half hour ago, and got the same behaviors. The vlamingii is all over the sailfin. I have the octoreef 150 running with the cup off
Fairy wrasse is in qt with the foxface. So out of harms way. The cloudiness is gone from his eyes and he did not enjoy me interrupting his bedtime.